RESPONSE OF THE PINEAL AND ADRENAL GLANDS TO SODIUM RESTRICTION1

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Abstract
Pineal fat stainable with oil red 0 was markedly depleted in intact and adrenalectomized rats maintained on a diet deficient in sodium. Pineal fat was mildly depleted by adrenalectomy alone. The zona glomerulosa of the adrenal gland widened in response to the sodium deficient regimen in both intact and pinealectomized rats. These alterations were taken to indicate that the pineal gland may elaborate a hormone which is involved in salt regulation.