3,4-Methylenedioxymethamphetamine (MDMA) neurotoxicity in rats: a reappraisal of past and present findings
Open Access
- 16 March 2006
- journal article
- review article
- Published by Springer Nature in Psychopharmacology
- Vol. 189 (4) , 407-424
- https://doi.org/10.1007/s00213-006-0322-6
Abstract
3,4-Methylenedioxymethamphetamine (MDMA) is a widely abused illicit drug. In animals, high-dose administration of MDMA produces deficits in serotonin (5-HT) neurons (e.g., depletion of forebrain 5-HT) that have been interpreted as neurotoxicity. Whether such 5-HT deficits reflect neuronal damage is a matter of ongoing debate.Keywords
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