Accurate, Wide-Range, Automated, High-Performance Liquid Chromatographic Method for the Estimation of Octanol/Water Partition Coefficients I: Effect of Chromatographic Conditions and Procedure Variables on Accuracy and Reproducibility of the Method
- 1 November 1984
- journal article
- research article
- Published by Elsevier in Journal of Pharmaceutical Sciences
- Vol. 73 (11) , 1616-1623
- https://doi.org/10.1002/jps.2600731133
Abstract
No abstract availableKeywords
This publication has 16 references indexed in Scilit:
- Accurate, Wide-Range, Automated, High-Performance Liquid Chromatographic Method for the Estimation of Octanol/ Water Partition Coefficients II: Equilibrium in Partition Coefficient Measurements, Additivity of Substituent Constants, and Correlation of Biological DataJournal of Pharmaceutical Sciences, 1984
- Synthesis and analysis of various 3-furyl ketones from Perilla frutescensJournal of Agricultural and Food Chemistry, 1984
- Alternative Methods Could Cut Animal Use in Toxicity TestsChemical & Engineering News, 1983
- Inhibitors of hepatic mixed-function oxidases. 4. Effects of benzimidazole and related compounds on aryl hydrocarbon hydroxylase activity from phenobarbitone and 3-methylcholanthrene induced ratsJournal of Medicinal Chemistry, 1982
- Structure-Activity Relationships and Drug DispositionAnnual Review of Pharmacology and Toxicology, 1981
- Correlation of biological activity and high-pressure liquid chromatographic retention index for a series of propranolol, barbiturate, and anthranilic acid analogsJournal of Medicinal Chemistry, 1979
- Computer-Assisted Computation of Partition Coefficients from Molecular Structures Using Fragment ConstantsJournal of Chemical Information and Computer Sciences, 1979
- Use of high-pressure liquid chromatography for quantitative structure-activity relationship studies of sulfonamides and barbituratesJournal of Medicinal Chemistry, 1976
- Direct measurement of octanol-water partition coefficients by high-pressure liquid chromatographyJournal of Medicinal Chemistry, 1976
- The Partition of Organic Compounds Between Higher Alcohols and Water.Acta Chemica Scandinavica, 1951