VASCULAR-RESPONSES IN EQUINE DIGIT

  • 1 January 1975
    • journal article
    • research article
    • Vol. 36  (8) , 1249-1253
Abstract
Digital circulation was isolated in 12 ponies under pentobarbital anesthesia. Blood flow was either controlled by a pump or measured under natural perfusion. Responses to rapid changes and stoppages of blood flow indicated no evidence of autoregulation or reactive hyperemia. Local administration of acetylcholine, histamine and prostaglandins E1 and E2 decreased prevenous resistance, whereas epinephrine and serotonin caused prevenous constriction. Large doses of epinephrine and serotonin decreased venous caliber. The effects of prostaglandins A1 and F2.alpha. were variable. The equine digital vasculature responded to changes in flow and to vasoactive agents like the canine forelimb skin vasculature.

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