Single base deletion in the vasopressin gene is the cause of diabetes insipidus in Brattleboro rats
- 1 April 1984
- journal article
- research article
- Published by Springer Nature in Nature
- Vol. 308 (5961) , 705-709
- https://doi.org/10.1038/308705a0
Abstract
In rats with hereditary hypothalamic diabetes insipidus (Brattleboro rats) the gene for the vasopressin precursor lacks a single G residue in the protein-coding region. The mutation gives rise to an open reading frame predicting a hormone precursor having a different C-terminus.Keywords
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