• 1 January 1985
    • journal article
    • review article
    • Vol. 12  (1) , 13-20
Abstract
Excluding the most frequent kinds of problems seen with the nonsteroidal antiflammatory drugs (NSAID) i.e., gastritis, peptic ulceration and renal effects, published reports indicate that these drugs may cause a wide variety of rare adverse reactions. The most serious of these are hypersensitivity reactions: blood dyscrasias (aplastic anemia, thrombocytopenia, agranulocytosis, hemolytic anemia), erythema multiforme and hepatitis. Aseptic meningitis and anaphylactoid reactions may strike patients with underlying immunologic abnormalities; urticaria, bronchospasm and proctocolitis may affect aspirin-sensitive patients. Other unusual reactions include several kinds of bullous dermatitis, febrile reactions, pneumonitis, esophageal ulceration, parotitis, pancreatitis and neurological or psychological effects.

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