Cysteamine as a Protective Agent with High-LET Radiations
- 1 May 1980
- journal article
- research article
- Published by JSTOR in Radiation Research
- Vol. 82 (2) , 290-296
- https://doi.org/10.2307/3575380
Abstract
The radiation protection of cysteamine for high-LET [linear energy transfer] radiations was measured with synchronized Chinese hamster V79 [lung fibroblast] cells. A high concentration (75 mM) of cysteamine provided protection against X rays and 90 and 170 keV/.mu.m He ions. The extent of protection decreased with increased LET value but was substantial with the highest-LET radiation. The approximate dose-modifying factor for G1/S cells was decreased from 4.8 to 1.6 and for late-S cells from 3.2 to 1.5. The shape of the high-LET survival curves for both cell cycle times was preserved as expected for a dose-modifying agent.This publication has 4 references indexed in Scilit:
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