A practical preparative scale synthesis of d/l‐6‐fluorodopa
- 1 September 1986
- journal article
- research article
- Published by Wiley in Journal of Labelled Compounds and Radiopharmaceuticals
- Vol. 23 (9) , 1019-1028
- https://doi.org/10.1002/jlcr.2580230914
Abstract
A practical preparative scale synthesis of D/L‐6‐fluorodopa (6‐FD) is presented. From veratric acid the procedure affords D/L‐6‐FD in 12% overall yield in 11 steps. Useful batch quantities ( > 300 mg) of this material were readily obtained and used as an analytical standard for 19F NHR and HPLC analyses in the preparation of L‐[18F]6‐fluorodopa.Keywords
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