Cardiovascular Responses of Unanesthetized Rats During Traumatic and Endotoxin Shock.

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Abstract
Summary The arterial pressures, heart rates and respiratory rates of unanesthetized rats have been recorded by direct measurement. The effects of traumatic shock and lethal dosages of endotoxin on these responses have been observed. The cardiovascular responses, symptoms and pathologic changes observed in rats subjected to trauma and to endotoxin intoxication were similar and, while certain differences have been observed, they are considered to be of insufficient magnitude to exclude endotoxins as possible factors concerned with their proposed role in irreversible shock.

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