OKT 6-POSITIVE CELLS - THEIR DEMONSTRATION IN HUMAN THYMUS, AND THE EFFECT OF FIXATION ON THE IMMUNOPEROXIDASE REACTION

  • 1 January 1982
    • journal article
    • research article
    • Vol. 106  (1) , 9-12
Abstract
Human thymocytes at an intermediate stage of differentiation were demonstrated in situ in tissue sections of thymus using the mouse monoclonal antibody OKT 6 THY and the immunoperoxidase technique. These cells resided mainly within the thymic cortex. The effects of on-slide fixation on the ease of demonstration of the antigen involved were assessed. The choice of fixative had a marked effect, acetone and paraformaldehyde producing the most satisfactory results.