Abstract
A review of the biochemistry of toxemia in man and lower animals, with emphasis on clinical significance. Diphtheria toxin is most frequently studied, but other bacterial toxins, CCl4, chloroform, P, organic arsenicals, guanidine, and eclampsia, are discussed. Evidence is discussed that toxaemia works its change in metabolism, especially that of carbohydrate metabolism, by damaging the liver and the endocrine glands.