EFFECT OF ANTIFIBRINOLYSIS TREATMENT ON HUMAN CANCER IN NUDE-MICE
- 1 January 1982
- journal article
- research article
- Vol. 2 (6) , 339-343
Abstract
The effect of tranexamic acid on the growth of 3 human tumor cell lines (lung squamous cell carcinoma QG-56, lung adenocarcinoma PC-12 and ovarian carcinoma OC-1) was investigated in vitro and in vivo in nude mice. Tranexamic acid exhibited no direct cytotoxicity in vitro, but it inhibited the growth of the 3 cell lines as tumors in nude mice. Prominent deposition of fibrin or fibrinogen around tumor cells at the advancing border was observed only in the tumors of treated animals.This publication has 10 references indexed in Scilit:
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