Effect of Postganglionic Sympathectomy on Canine Gastric Secretion

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Abstract
The secretory characteristics of canine mucosal septal (vagally innervated, Hollander-Jemerin type) and separated (vagally denervated, Heidenhain type) gastric pouches were studied before and after postganglionic sympathectomy. The tests of secretion included the max. secretory capacity of the pouches when stimulated by histamine, the vol., acidity and pepsin content of the juice secreted during fasting, and the vol., acidity and pepsin content of the juice obtained in response to standard doses of histamine and urecholine and to test meals of meat and alcohol. The results allow the conclusion that the sympathetic nerves which reach the stomach do not exert a direct effect on the secretion of acid or pepsin by the gastric mucosa.