In Vitro Susceptibilities of Zygomycetes to Combinations of Antimicrobial Agents
Open Access
- 1 August 2002
- journal article
- research article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 46 (8) , 2708-2711
- https://doi.org/10.1128/aac.46.8.2708-2711.2002
Abstract
Combinations of antimicrobial agents were tested against 35 strains of zygomycetes. The interaction between amphotericin B and rifampin was synergistic or additive. Flucytosine alone was inactive and, upon combination with amphotericin B, synergy was not achieved. The combination of amphotericin B with terbinafine was synergistic for 20% of strains, and the interaction between terbinafine and voriconazole was synergistic for 44% of strains. Antagonism was not observed.Keywords
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