A combined experiment‐computer technique for determining heating programs for batch and continuous freeze dryers

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Abstract
Summary: Two parameters, which characterize the freeze drying process, are obtained by a linear regression of variables derived from data from a limited number of freeze drying experiments. Freeze drying times and sample temperature profiles can then be simulated for other processing conditions, using computer techniques. The simulation has been used to predict the drying behaviour of skim milk samples for a continuous freeze drying process. The results of the simulation agree closely with a batch freeze drying operated so as to model a continuous process.