URINARY AND GENITAL TRACT PHOSPHATASES OF THE MALE DUTCH RABBIT

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Abstract
Alkaline and acid phosphatase activity of genital tract tissue extracts and of urine collected under several conditions from male Dutch rabbits was detd. using the Huggins and Talalay technic. There was a wide range of values for the appreciable amt. of alkaline phosphatase found in male rabbit urine. Probably due to the decrease in normal seminal secretions, estrogen-treated rabbits did not show high values (above 30 units/100 ml. urine). As a rule, there was no appreciable acid phosphatase activity in un-contaminated urine. All accessories studied, as well as the testis-epididymis, and especially the prostate-vesicular gland, contained some acid phosphatase. Alkaline phosphatase was present in large amts. in the testis-epididymis, and generally in the seminal vesicle, and represented a possible source of the high enzyme activity found in the urines of some normal and androgen-treated rabbits. Urine collected under conditions allowing contamination with food or feces did not provide a reliable picture of phosphatase activities.