A Further Study of the Kveim Reaction in Sarcoidosis and Tuberculosis

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Abstract
IN our experience, the Kveim reaction has not been a reliable aid in the diagnosis of sarcoidosis.1 , 2 Nevertheless, enthusiastic reports concerning its specificity continue to appear. James and Thomson3 found the Kveim test positive in 12 of 16 patients with clinical evidence of sarcoidosis, and negative in 47 subjects with other diseases. Nelson and Schwimmer4 obtained positive results in 74 per cent of 53 patients with sarcoidosis; only 1 positive test was observed among 99 patients with tuberculosis, and no positive tests among 100 other control subjects.In an effort to duplicate these results, we have carried out another series . . .