TUMOR-PRODUCING EFFECT OF AUTOMOBILE EXHAUST CONDENSATE AND FRACTIONS THEREOF .2. ANIMAL STUDIES
- 1 January 1978
- journal article
- research article
- Vol. 1 (6) , 737-746
Abstract
The induction of squamous cell carcinomas and papillomas in a total of 1,950 mice in a lifelong skin-dropping experiment with different doses of automobile exhaust condensate and its fractions is described. The dose-response studies indicate that local oncogenic activity of automobile condensate is contained primarily in its polycyclic aromatic hydrocarbon-fractions. Findings in lung tumor incidences are given. Results of the sebaceous gland suppression screening test were comparable to findings of the skin-dropping experiments.This publication has 3 references indexed in Scilit:
- TUMOR-PRODUCING EFFECT OF AUTOMOBILE EXHAUST CONDENSATE AND FRACTIONS THEREOF .3. MATHEMATICAL-STATISTICAL EVALUATION OF THE TEST-RESULTS1978
- TUMOR-PRODUCING EFFECT OF AUTOMOBILE EXHAUST CONDENSATE AND FRACTIONS THEREOF .1. CHEMICAL STUDIES1978
- Evaluation of six short term tests for detecting organic chemical carcinogens and recommendations for their useNature, 1976