Demonstration in situ of “T” Cells and “T” Cell Subsets in Lichen Planus using Monoclonal Antibodies

Abstract
An in situ demonstration of T lymphocytes and T lymphocyte subsets in tissue sections using a model case of lichen planus, is described. Indirect immunoperoxidase with monoclonal antibodies to T cells and T cell subsets is used. In the case examined a predominance of helper T cells was found. The potential application of this method in the immunopathology of skin and internal organs is discussed.