Immunoblotting and Enzyme-Linked Immunosorbent Assay Analysis of Serological Responses in Patients Infected with Herpes Simplex Virus Types 1 and 2
- 1 January 1985
- journal article
- research article
- Published by S. Karger AG in Intervirology
- Vol. 24 (1) , 18-25
- https://doi.org/10.1159/000149614
Abstract
Serological responses to soluble membrane and cytoplasmic antigens specified by herpes simplex virus type 1 (HSV1) and 2 (HSV2) were studied by immunoblotting and by ELISA. In the immunoblotting test, polypeptides migrating like the HSV1-specified glycoprotein C showed type-specific reactivity but could not always be detected. The immunoblotting and ELISA results were in agreement when antibody responses to HSV1- and HSV2-specified antigens were compared, and they allowed the identification of patients with HSV2 and/or HSV1 antibodies.Keywords
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