1,4-Dioxene(2,3-dihydro-1,4-dioxine) in organic synthesis. Part 9. Preparation of biologically active side-chains from 17-oxosteroids
- 1 January 1990
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Perkin Transactions 1
- No. 4,p. 1107-1110
- https://doi.org/10.1039/p19900001107
Abstract
Steroidal 17α-2,3-dihydro-1,4-dioxin-6-yl)-17β-ols of type (2), readily available from 17-oxo steroids and 2 3-dihydro-1,4-dioxine, are easily converted into 21-hydroxy-20-oxo steroids with or without a double bond at the 16(17) position as well as to the dihydroxyacetone side-chain.Keywords
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