The plasma protease inhibitor system (Pi) of Standardbred horses
- 31 July 1984
- journal article
- research article
- Published by Wiley in Animal Blood Groups and Biochemical Genetics
- Vol. 15 (3) , 191-206
- https://doi.org/10.1111/j.1365-2052.1984.tb01116.x
Abstract
The plasma protease inhibitor system (Pi) of standardbred horses was studied by thin-layer, high-voltage, acid polyacrylamide gel electrophoresis (pH 4.6) followed by protein staining and staining for trypsin and chymotrypsin inhibition. In addition to the 8 thoroughbred alleles (PiF, G, I, L, N, S1, S2, U), another 10 alleles, designated (PiH, J, K, O, P, Q, R, V, X, Z), were postulated to account for the 98 Pi types which were observed in standardbreds. Detailed inhibitory spectra of the new alleles were determined and further exceptions to the Pi1, Pi2 classification of Juneja et al. were found. Limited family data demonstrated the genetic nature of the new variants and confirmed the allelic inheritance of the new Pi variants.Keywords
This publication has 17 references indexed in Scilit:
- Genetic polymorphism and close linkage of two α1-protease inhibitors in horse serumAnimal Blood Groups and Biochemical Genetics, 2009
- Protease inhibitor system in horses: classification and detection of a new alleleAnimal Blood Groups and Biochemical Genetics, 2009
- Characterisation of the α1-protease inhibitor system in Thoroughbred horse plasma by horizontal two-dimensional (ISO-DALT) electrophoresis. 1. Protein stainingAnimal Blood Groups and Biochemical Genetics, 2009
- Isoelectric focusing of horse acidic prealbumins on thin-layer polyacrylamide gelsAnimal Blood Groups and Biochemical Genetics, 2009
- A new allele in the prealbumin system of horse serum markersAnimal Blood Groups and Biochemical Genetics, 2009
- Characterisation of the α1‐protease inhibitor system in Thoroughbred horse plasma by horizontal two‐dimensional (ISO‐DALT) electrophoresis. 2. Protease inhibitionAnimal Blood Groups and Biochemical Genetics, 1983
- Irregular transmissions in the acidic prealbumin (Pr) system of the horseAnimal Blood Groups and Biochemical Genetics, 1980
- Isoelectric focusing of horse serum esterase isozymes and detection of new phenotypesAnimal Blood Groups and Biochemical Genetics, 1978
- Characterization of Natural Inhibitors of Trypsin and Chymotrypsin by Electrophoresis in Acrylamide-Agarose GelsNature, 1968
- The genetics of transferrins in cattleHeredity, 1965