SARCOIDOSIS - A CLINICAL REVIEW OF 111 CASES

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Abstract
The clinical course of sarcoidosis has been reviewed briefly on the basis of 111 patients seen at the Fitzsimons General Hospital between the years 1952 and 1960. It was noted that approximately 25 per cent of the patients in the series were asymptomatic and remained asymptomatic. The symptomatology coincided well with that in previous series, although it was noted that arthralgia or arthritis occurred in 10 per cent. The diagnosis is difficult to establish and depends on compatible clinical, histologic, and immunologic findings. Recurrences and exacerbations are noteworthy only because of their absence. Recovery, with apparent inactivity of the disease, was seen in 65 per cent; 24 per cent recovered with only minimal symptoms on the basis of residual fibrosis. Tuberculosis developed in 2 of 54 patients. The accurate evaluation of therapy was not possible, but the impression was gained that corti-costeroids afforded no benefit except the temporary amelioration of acute symptoms. The frequency of residual fibrosis appeared unaffected by steroid therapy.

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