A Microbiological Assay for Penicillic Acid
- 1 June 1978
- journal article
- research article
- Published by Elsevier in Journal of Food Protection
- Vol. 41 (6) , 432-434
- https://doi.org/10.4315/0362-028x-41.6.432
Abstract
Six bactertial cultures were studied in a search for an organism sensitive to penicillic acid suitable for use in a quantitative bioassay of this mycotoxin. A vegetative culture and a commercially prepared spore suspension of Bacillus subtilis were both sensitive to as little as 1 μg of penicillic acid and exhibited a linear relationship between 1 and 100 μg. The bioassay method was comparable in accuracy to thin layer chromatographic assay. The procedure was used to verify the biological activity of sample extracts, as well as to quantitate penicillic acid concentration in samples of liquid media and corn. The bioassay is sensitive, rapid (15–17 h), simple and inexpensive.This publication has 2 references indexed in Scilit:
- Stability of patulin and penicillic acid in fruit juices and flourJournal of Agricultural and Food Chemistry, 1968
- Activities of Twenty-two Antibacterial Substances against Nine Species of BacteriaJournal of Bacteriology, 1947