Adjuvant Activity of 6-Amino-6-Deoxy-Muramyldipeptides and Their Acylamino Derivatives on the Induction of Delayed Hypersensitivity to Azobenzenearsonate- N -Acetyl- l -Tyrosine in Guinea Pigs
- 1 June 1981
- journal article
- research article
- Published by American Society for Microbiology in Infection and Immunity
- Vol. 32 (3) , 1305-1308
- https://doi.org/10.1128/iai.32.3.1305-1308.1981
Abstract
The 6-amino-6-deoxy-N-acetylmuramyldipeptides and their 6-acylamino derivatives were shown to be active as adjuvants on the induction of delayed-type hypersensitivity to azobenzenearsonate-N-acetyl-l-tyrosine in guinea pigs. However, 6-acylamino-6-deoxy-N-(acyl)muramyldipeptides were inactive as adjuvants.This publication has 26 references indexed in Scilit:
- Adjuvant Activity of Nocardomycoloyl Derivatives of N-Acetylmuramyldipeptide in Mice and Guinea PigsMicrobiology and Immunology, 1980
- Synthesis of N-acetyl-6-amino- and -6-(acylamino)-6-deoxymuramoyl dipeptides, and their immunoadjuvant activitiesCarbohydrate Research, 1980
- Synthesis and immunoadjuvant activities of muramoyl-L-alanyl-D-isoglutamine and some carbohydrate analogsCarbohydrate Research, 1980
- In vitro spleen cell responsiveness to various analogs of MDP (N-acetylmuramyl-l-alanyl-d-isoglutamine), a synthetic immunoadjuvant, in MDP high-responder miceCellular Immunology, 1978
- IMMUNOADJUVANT ACTIVITIES OF SYNTHETIC 6-O-ACYL-N-ACETYLMURAMYL-L-ALANYL-D-ISOGLUTAMINE WITH SPECIAL REFERENCE TO EFFECT OF ITS ADMINISTRATION WITH LIPOSOMES1977
- RELATIONSHIP BETWEEN CHEMICAL-STRUCTURE AND ADJUVANT ACTIVITY OF SOME SYNTHETIC ANALOGS OF N-ACETYL-MURAMYL-L-ALANYL-D-ISOGLUTAMINE (MDP)1977
- EFFECT OF REPLACEMENT OF L-ALANINE RESIDUE BY GLYCINE, L-SERINE OR D-ALANINE IN AN N-ACETYLMURAMYL-L-ALANYL-D-ISOGLUTAMINE ON IMMUNOADJUVANCIES OF MOLECULES1977
- Correlation of structure and adjuvant activity of N-acetyl muramyl-L-alanyl-D-isoglutamine (MDP), its derivatives and analogues. Anti-adjuvant and competition properties of stereoisomersBiochemical and Biophysical Research Communications, 1976
- Immunoadjuvant activities of synthetic N-acetyl-muramyl-peptides or -amino acids.1975
- Minimal structural requirements for adjuvant activity of bacterial peptidoglycan derivativesBiochemical and Biophysical Research Communications, 1974