Expression of the teratocarcinoma phenotype in hybrids between totipotent mouse teratocarcinoma and myeloma cells
- 1 October 1980
- journal article
- research article
- Published by Wiley in Journal of Cellular Physiology
- Vol. 105 (1) , 73-79
- https://doi.org/10.1002/jcp.1041050110
Abstract
We have produced somatic cell hybrids between totipotent mouse teratocarcinoma and myeloma cells. These hybrids behave like the teratocar‐cinoma cell parent and express teratocarcinoma embryonal antigens. However, they also express the myeloma H‐2 antigens. The availability of these hybrids should make it possible to study the expression of already rearranged immunoglobulin genes during mouse development.Keywords
This publication has 25 references indexed in Scilit:
- Somatic cell hybrids between totipotent mouse teratocarcinoma and rat hepatoma cellsJournal of Cellular Physiology, 1979
- Activation of teratocarcinoma-derived hemoglobin genes in teratocarcinoma-friend cell hybridsCell, 1978
- Hemoglobin synthesis in cell hybrids formed between teratocarcinoma and friend erythroleukemia cellsCell, 1977
- Teratocarcinoma × friend erythroleukemia cell hybrids resemble their pluripotent embryonal carcinoma parentDevelopmental Biology, 1977
- Derivation of specific antibody‐producing tissue culture and tumor lines by cell fusionEuropean Journal of Immunology, 1976
- ABSENCE OF SEROLOGICALLY DETECTABLE H-2 ON PRIMITIVE TERATOCARCINOMA CELLS IN CULTURETransplantation, 1974
- A RAPID BANDING TECHNIQUE FOR HUMAN CHROMOSOMESThe Lancet, 1971
- Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4Nature, 1970
- The use of drug-resistant markers to study the hybridization of mouse fibroblastsExperimental Cell Research, 1966
- Selection of Hybrids from Matings of Fibroblasts in vitro and Their Presumed RecombinantsScience, 1964