Abstract
If an enzymic reaction is inhibited by its products at the concentrations which normally occur during the reaction, the kinetic analysis must include an integrated form of the rate equation. The integrated equation is presented in a form which is analogues to the Michaelis equation. The initial velocity, vo, is replaced by the average velocity, v, and the starting substrate concentration, So , by the average concentration, S = So/f. Factor f is tabulated as a function of the degree of cleavage, o. The methods for the graphic evaluation of the integrated equation are discussed.

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