Objective Evaluation of the Intensity of Shock Induced by Antiplatelet Serum in the Dog
- 1 June 1954
- journal article
- research article
- Published by American Physiological Society in American Journal of Physiology-Legacy Content
- Vol. 177 (3) , 515-522
- https://doi.org/10.1152/ajplegacy.1954.177.3.515
Abstract
Hematolog-ical detns., C02 and O2 in arterial and venous blood, lactic acid, P and glucose in the whole blood, pH, plus detns. of arterial pressure, were carried out on 26 dogs subjected to shock produced by APS (anti-platelet serum), and on 7 control animals. Analysis of the results demonstrated that it is possible to classify degree of shock in 3 categories (mild, moderate and severe) when the biochemical and hematological data and detns. of blood gases are taken in conjunction with the survival time of the animals involved. Thus, an objective criterion for the study of this type of shock can be presented; such a criterion, in fact, is judged indispensable for a rational interpretation of the results. The biochemical and gasometric observations of the blood of dogs subjected to shock induced by anti-platelet serum were shown to be similar to corresponding figures found in the literature on exptl. hemorrhagic and traumatic shock, or to data on human cases, thus indicating a close resemblance of all these pathological states.Keywords
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