TOLERANCE IN ADULT RABBITS BY REPEATED NON-IMMUNOGENIC DOSES OF BOVINE SERUM ALBUMIN
- 1 January 1967
- journal article
- research article
- Vol. 13 (2) , 141-+
Abstract
A series of multiple intravenous injections of bovine serum albumin, starting with doses too small to be immuno-genic, was used for the induction of tolerance in adult rabbits. With normal outbred animals, approximately 50% of the rabbits were rendered completely tolerant by an injection schedule with 0.1 mg as the initial dose and a total dose of 9 mg given over a period of 5-7 weeks. The mechanism of this "low-dose tolerance" is discussed.This publication has 13 references indexed in Scilit:
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