Inhibitory Effect of Urografin 76 on Platelet Function and Thrombus Formation in Vascular Catheters
- 1 April 1980
- journal article
- research article
- Published by SAGE Publications in Angiology
- Vol. 31 (4) , 283-290
- https://doi.org/10.1177/000331978003100408
Abstract
The effect of Urografin 76 on platelet aggregation and thrombus formation in vascular catheter was studied. In vitro experiments revealed that ADP-, epinephrine-, and collagen-induced platelet aggregation was significantly inhibited by Urografin 76 in concentrations greater than 0.3, 1, and 5% respectively. Rabbits that received 10 ml of Urografin 76 demonstrated a transient decrease in platelet aggregation for at least 3 minutes. Urografin 76 was apparently more effective than saline in preventing blood clot formation.Keywords
This publication has 23 references indexed in Scilit:
- Thromboembolic Complications in Coronary AngiographyActa Radiologica. Diagnosis, 1977
- Influence of Cholografin and Renografin 76 on Platelet FunctionRadiology, 1977
- Percutaneous catheter emboli: Sources and preventionCatheterization and Cardiovascular Diagnosis, 1976
- Effect of Contrast Agents on Platelet Aggregation and14C-Serotonin ReleaseNew England Journal of Medicine, 1974
- Contrast Material Used as a Catheter Flushing Agent: A Method to Reduce Clot Formation During AngiographyRadiology, 1974
- Arterial Thrombus Formation During Clinical Percutaneous CatheterizationCirculation, 1970
- Platelet Adhesion and Aggregation Following Contact between Blood and Vascular Catheters in vitroScandinavian Journal of Haematology, 1969
- Platelet Adhesion and Thrombus Formation on Vascular Catheters in DogsActa Radiologica. Diagnosis, 1969
- ALTERATION OF COAGULATION MECHANISM OF BLOOD BY CONTRAST MEDIAAmerican Journal of Roentgenology, 1968
- Anticoagulant Activity of Angiographic Contrast MediaInvestigative Radiology, 1966