NEW VARIANTS OF ALPHA-1-ANTITRYPSIN - COMPARISON OF PI TYPING TECHNIQUES
- 1 January 1981
- journal article
- research article
- Vol. 33 (3) , 354-365
Abstract
Four new rare inherited [human] variants (Pi types) of .alpha.1-antitrypsin (.alpha.1-protease inhibitor) are described. Each variant was compared with previously reported genetic variants by several techniques used for Pi typing: isoelectric focusing in polyacrylamide gel; starch gel electrophoresis and agarose gel electrophoresis. Some variants are identical or very similar by 1 technique but can be clearly distinguished by another technique. Crossed immunoelectrophoresis and gel immunofixation were used to identify the gel bands as .alpha.1-antitrypsin.This publication has 36 references indexed in Scilit:
- [Study of genetic variants of alpha 1-antitrypsin in bidimensional immuno-electrofocusing].1974
- ?1? Polymorphism of a Bantu population: Description of a mew allele PiLHuman Genetics, 1974
- PiB, a new allele of alpha1 antitrypsin genetic variants.1973
- α 1 -Antitrypsin Deficiency: A Variant with No Detectable α 1 -AntitrypsinScience, 1973
- Techniques d'identification des groupes Pi: Premières statistiques languedociennesRevue Française de Transfusion Et Immuno-Hématologie, 1972
- Electroimmuno AssayScandinavian Journal of Clinical and Laboratory Investigation, 1972
- Quantitative Studies on the Inherited Variants of Serum α1-antitrypsinScandinavian Journal of Clinical and Laboratory Investigation, 1969
- The Pi Phenotype MPVox Sanguinis, 1968
- The polymorphism of “prealbumins” and α1-antitrypsin in human seraClinica Chimica Acta; International Journal of Clinical Chemistry, 1967
- HEREDITARY VARIANTS OF SERUM ALPHA1-ANTITRYPSIN1965