Genomic footprinting with Taq polymerase
- 1 March 1989
- journal article
- Published by Springer Nature in Nature
- Vol. 338 (6212) , 277
- https://doi.org/10.1038/338277a0
Abstract
The linear amplification of chemically sequenced DNA with DNA polymerase from Thermus aquaticus permits the direct detection of DNA methylation and protein-DNA interaction sites in vivo.Keywords
This publication has 11 references indexed in Scilit:
- [57] Sequencing end-labeled DNA with base-specific chemical cleavagesPublished by Elsevier ,2004
- Genomic sequencing and in vivo footprinting of an expression-specific DNase I-hypersensitive site of avian vitellogenin II promoter reveal a demethylation of a mCpG and a change in specific interactions of proteins with DNA.Proceedings of the National Academy of Sciences, 1988
- Genomic footprinting reveals cell type-specific DNA binding of ubiquitous factorsCell, 1987
- The use of permanganate as a sequencing reagent for identification of 5-methylcytosine residues in DNANucleic Acids Research, 1987
- Enzymatic Amplification of β-Globin Genomic Sequences and Restriction Site Analysis for Diagnosis of Sickle Cell AnemiaScience, 1985
- Molecular Biology of DNA MethylationPublished by Springer Nature ,1985
- Use of light for footprinting DNA in vivoNature, 1984
- Genomic sequencing.Proceedings of the National Academy of Sciences, 1984
- DNA MethylationPublished by Springer Nature ,1984
- Pyrimidine-specific chemical reactions useful for DNA sequencingNucleic Acids Research, 1980