CHANGES IN RENAL FUNCTIONS ASSOCIATED WITH DIABETES INSIPIDUS PRECIPITATED BY ANTERIOR HYPOTHALAMIC LESIONS
- 31 January 1950
- journal article
- research article
- Published by American Physiological Society in American Journal of Physiology-Legacy Content
- Vol. 160 (2) , 321-324
- https://doi.org/10.1152/ajplegacy.1950.160.2.321
Abstract
With the development of diabetes insipidus following the anatomical destruction of the neurohypophysis without damage to the adenohypophysis, glomerular filtration rate, renal plasma flow and the maximal rate of transfer of dextrose, all decrease 50% or more. These changes are proportional and are believed to be caused by the inactivation of nephrons with the development of diabetes insipidus. This may be an additional mechanism for conserving water, since it seems to operate in normal animals subjected to moderate dehydration.Keywords
This publication has 3 references indexed in Scilit:
- PROPORTIONAL CHANGES IN RENAL TUBULAR REABSORPTION OF DEXTROSE AND EXCRETION OF P-AMINOHIPPURATE WITH CHANGES IN GLOMERULAR FILTRATIONAmerican Journal of Physiology-Legacy Content, 1949
- SOME ENDOCRINE INFLUENCES ON RENAL FUNCTION AND CARDIAC OUTPUTAmerican Journal of Physiology-Legacy Content, 1947
- EFFECTS OF THE REMOVAL OF THE ANTERIOR LOBE OF THE HYPOPHYSIS ON SOME RENAL FUNCTIONSAmerican Journal of Physiology-Legacy Content, 1942