MULTIPLE-MYELOMA AND AMYLOID BONE-LESIONS COMPLICATING RHEUMATOID-ARTHRITIS

  • 1 January 1981
    • journal article
    • research article
    • Vol. 8  (5) , 845-850
Abstract
Multiple myeloma developed in a woman with a 7-yr history of seropositive rheumatoid arthritis (RA). An unexpected finding was the presence of massive amyloid deposits in the left femur and traces of amyloid in the synovium. Detailed histopathologic studies conclusively excluded amyloid arthropathy. Although definitive tissue classification was not possible, this patient in all likelihood had 2 types of amyloid: massive bone lesions of myeloma-associated (AL) amyloid and focal subsynovial deposits of RA-associated secondary (AA) amyloid.