Theoretically-derived molecular descriptors important in human intestinal absorption
- 21 March 2001
- journal article
- Published by Elsevier in Journal of Pharmaceutical and Biomedical Analysis
- Vol. 25 (2) , 227-237
- https://doi.org/10.1016/s0731-7085(00)00492-1
Abstract
No abstract availableKeywords
This publication has 19 references indexed in Scilit:
- Hormonal regulation of oligopeptide transporter Pept-1 in a human intestinal cell lineAmerican Journal of Physiology-Cell Physiology, 1999
- Prediction of Membrane Permeability to Peptides from Calculated Dynamic Molecular Surface PropertiesPharmaceutical Research, 1999
- A contribution to safety assessment of veterinary drug residues: in vitro / ex vivo studies on the intestinal toxicity and transport of covalently bound residuesXenobiotica, 1999
- Evaluation of Dynamic Polar Molecular Surface Area as Predictor of Drug Absorption: Comparison with Other Computational and Experimental PredictorsJournal of Medicinal Chemistry, 1998
- Intestinal Drug Absorption and Metabolism in Cell Cultures: Caco-2 and BeyondPharmaceutical Research, 1997
- Theoretical Calculation and Prediction of Caco-2 Cell Permeability Using MolSurf Parametrization and PLS StatisticsPharmaceutical Research, 1997
- Polar Molecular Surface Properties Predict the Intestinal Absorption of Drugs in HumansPharmaceutical Research, 1997
- Caco-2 monolayers in experimental and theoretical predictions of drug transportAdvanced Drug Delivery Reviews, 1996
- Evidence for Glucuronide Conjugation of p-Nitrophenol in the Caco-2 Cell ModelPharmaceutical Research, 1991
- Estimating Human Oral Fraction Dose Absorbed: A Correlation Using Rat Intestinal Membrane Permeability for Passive and Carrier-Mediated CompoundsPharmaceutical Research, 1988