A Women's Birth Cohort Effect on Malformation Rates

Abstract
A relatively sudden increase in prevalence at birth of gastroschisis was seen in Sweden at the beginning of the 1970''s. Case-control studies, looking for a teratogenic factor, have proved negative. The women''s birth cohort apparently has an effect: women born in 1953-1955 have an increased probability of having this type of malformed infant. A computer simulation is made indicating that the actually recorded facts can, at least in part, be explained by the hypothesis.

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