ORGANIC REACTIONS WITHOUT SOLVENT: MICHAEL ADDITIONS ON AN UNSATURATED SULFONE AND SULFOXIDE
- 1 September 1988
- journal article
- research article
- Published by Taylor & Francis in Phosphorus and Sulfur and the Related Elements
- Vol. 39 (1) , 73-78
- https://doi.org/10.1080/03086648808072857
Abstract
Solid-liquid phase transfer catalysis in the absence of any solvent efficiently promotes Michael additions of nitro alkanes and of diethyl N-acetylaminomalonate to phenyl vinyl sulfone and to phenyl vinyl sulfoxide. The adduct of the Michael addition to diethyl N-acetylaminomalonate to phenyl vinyl sulfoxide was converted by distillation under partial vacuum to diethyl N-acetylamino vinyl malonate which gave (±)-vinylglycine by hydrochloric acid catalysis.Keywords
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