Biosynthesis of 17β-estradiol and Its Binding to Specific Receptors in Human Gingiva

Abstract
An increased biosynthesis of 17β-estradiol was found by microsomes obtained from the inflamed human gingivae when compared to those from healthy and hyperplastic tissues. In contrast, binding of estradiol to cytoplasmic receptors was increased only in hyperplastic tissue and was independent of the amount of estradiol formed.