Effect of Kidney Shielding on Survival Following Whole Body Irradiation

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Abstract
Thirty day survivals following 650 r whole body irradiation to 2 unprotected groups of rats were 20.4% and 28.5%,respectively. Lead shielding of the following structures increased the survival to the figure indicated: kidneys alone, 64.4%; superficial back structures alone, 85.7%; kidneys and superficial back structures, 70.0%. Protection was attributed to a nonspecific beneficial effect of any shielded tissue. A locally raised strain of Wistar rats proved to be more sensitive to irradiation than did a commercial strain of Sprague-Dawley rats.