THE RELATION BETWEEN TOXICITY AND TOXIN-RELATED-ANTIGEN CONTENTS OF CLOSTRIDIUM BOTULINUM TYPES C AND D CULTURES AS DETERMINED BY MOUSE BIOASSAY AND ELISA
- 1 January 1982
- journal article
- research article
- Published by Editorial Committee of Japanese Journal of Infectious Diseases, National Institute of Infectious Dis in Japanese Journal of Medical Science and Biology
- Vol. 35 (5-6) , 203-211
- https://doi.org/10.7883/yoken1952.35.203
Abstract
Enzyme-linked immunosorbent assay (ELISA) was tested for the ability to differentiate between botulinum type C1 and D toxins. The results indicate an antigenic relationship between type C1 and D toxins. Indications were obtained that the antigenicities of type C1 and of D toxins produced by different strains are not identical. Although ELISA can be used to differentiate type C1 and D toxins from those of other types, the assay has only limited value to differentiate between type C1 and D toxins. No parallel relationship between toxicity (mouse bioassay) and toxin-related-antigen contents (ELISA) of Clostridium botulinum type C and D cultures was found.This publication has 11 references indexed in Scilit:
- Antigenic similarity of toxins produced by Clostridium botulinum type C and D strainsInfection and Immunity, 1980
- Noncorrelation between mouse toxicity and serologically assayed toxin in Clostridium botulinum type A culture fluidsApplied and Environmental Microbiology, 1979
- Enzyme-linked immunosorbent assay for detection of Clostridium botulinum type E toxinApplied and Environmental Microbiology, 1979
- ENZYME LINKED IMMUNOSORBENT ASSAY (ELISA) FOR DETECTION OF CLOSTRIDIUM BOTULINUM TYPE B TOXINJapanese Journal of Medical Science and Biology, 1979
- Acid precipitation of Clostridium botulinum type C and D toxins from whole culture by addition of ribonucleic acid as a precipitation aidInfection and Immunity, 1978
- ENZYME LINKED IMMUNOSORBENT ASSAY (ELISA) FOR DETERMINATION OF STAPHLOCOCCUS-AUREUS ENTEROTOXIN TYPE-B1978
- ENZYME-LINKED IMMUNOSORBENT ASSAY FOR DETECTION OF CLOSTRIDIUM BOTULINUM TOXIN TYPE AJapanese Journal of Medical Science and Biology, 1978
- Clostridium botulinum type D toxin: purification, molecular structure, and some immunological propertiesInfection and Immunity, 1977
- The isolation of IgG from mammalian sera with the aid of caprylic acidArchives of Biochemistry and Biophysics, 1969