Thirst-reducing effects of water by stomach fistula vs. water by mouth measured by both a consummatory and an instrumental response.

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Abstract
The effects of immediately prior drinking of water or injection of water directly into the stomach by fistula on the subsequent water drinking or lever pressing of thirsty rats were studied. Both direct stomach loading and prior drinking reduced consummatory drinking responses and also lever pressing; the inhibitory effect of drinking was greater than that of fistula injection. It is concluded "that mechanisms regulating thirst are located in both the mouth-throat and the stomach-intestine.".

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