Lipoprotein Lipase Activity of Rat and Human Placenta.

Publisher Website
Google Scholar
Abstract
Summary Lipoprotein lipase activity was found to be present in homogenates of placentas of rats pregnant 18–21 days and of human placentas obtained post partum. In the rat, the LPL activity in placenta was equal to that in heart, but much less than that found in adipose tissue. LPL activity in human placenta was smaller than that in rat placenta. Placental lipase activity was inhibited by DFP, protamine and 1 M NaCl, and considerably reduced in the absence of serum in the incubating medium. LPL activity in placenta may be related to the vascularity of this organ and may act to supply the fetus with fatty acids by hydrolyzing lipoproteins obtained from the maternal circulation.