Serum Osmolality

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Abstract
SERUM osmolality is a simple and widely available laboratory measurement, but its specific usefulness in clinical medicine is often misunderstood. The test for serum osmolality is ordered most commonly to assist in the evaluation of hyponatremia.1 2 3 4 5 6 However, it is not often recognized dial the test is of limited use in this disorder; without knowledge of the question being addressed by the measurement of serum osmolality, physicians may be misled by the test results in certain instances. The serum osmolality measurement has two specific uses. The first is to determine whether serum water content deviates widely from normal. The second is . . .