Targeting signal transduction in the discovery of antiproliferative drugs
Open Access
- 31 December 1996
- journal article
- review article
- Published by Elsevier in Chemistry & Biology
- Vol. 3 (11) , 887-893
- https://doi.org/10.1016/s1074-5521(96)90177-5
Abstract
No abstract availableKeywords
This publication has 26 references indexed in Scilit:
- PD 098059 Is a Specific Inhibitor of the Activation of Mitogen-activated Protein Kinase Kinase in Vitro and in VivoJournal of Biological Chemistry, 1995
- Desensitization of Ras Activation by a Feedback Disassociation of the SOS-Grb2 ComplexJournal of Biological Chemistry, 1995
- Mitogen-activated Protein Kinase Kinase Inhibition Does Not Block the Stimulation of Glucose Utilization by InsulinJournal of Biological Chemistry, 1995
- Tyrosine Kinase Inhibition: An Approach to Drug DevelopmentScience, 1995
- NMR structure of the N-terminal SH3 domain of GRB2 and its complex with a proline-rich peptide from SosNature Structural & Molecular Biology, 1994
- Proteins regulating Ras and its relativesNature, 1993
- Normal and oncogenic p21ras proteins bind to the amino-terminal regulatory domain of c-Raf-1Nature, 1993
- Binding of a high affinity phosphotyrosyl peptide to the Src SH2 domain: Crystal structures of the complexed and peptide-free formsCell, 1993
- SH2 domains recognize specific phosphopeptide sequencesPublished by Elsevier ,1993
- An Insulin-Stimulated Protein Kinase Similar to Yeast Kinases Involved in Cell Cycle ControlScience, 1990