CANDIDA-TROPICALIS VULVOVAGINITIS

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  • 1 January 1985
    • journal article
    • research article
    • Vol. 66  (2) , 229-232
Abstract
In a majority of patients with candidal vulvovaginitis, drug therapy is convenient and effective. A small but significant group of patients remain symptomatic with recurrent, chronic candidiasis. A study of 805 patients was undertaken to delineate microbiologically candidal species. The recurrence rate for C. tropicalis was twice the rate for C. albicans despite continuous medical care and multiple therapies [miconazole cream, clotrimazole cream, aqueous gentian iodine, ketoconazole, amphotericin, vagitrol and nystatin], the recurrent C tropicalis patients remained symptomatic with persistence of the organism. The difficulty encountered with eradication of C tropicalis may have been due to the lack of susceptibility of the cell membrane to the commonly used antifungal agents.