THE DISPLACEMENT OF SERUM WATER BY THE LIPIDS OF HYPERLIPEMIC SERUM. A NEW METHOD FOR THE RAPID DETERMINATION OF SERUM WATER 1

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Abstract
Misleadingly low concentrations of electrolytes were found in the sera of patients with markedly lacticent sera. After removal of insoluble lipids by ultracentrifugation, concentrations of electrolytes were normal or nearly so. This shows the desirability of expressing electrolytes in terms of serum water. A new method for the rapid determination of serum water is described. It is based on the change in freezing point caused by the addition of a known amount of dry NaCl to serum. At Fiske Associates (Boston) freezing point osmometer is used. The method checks within 1 g% with the gravimetric method.