Restoration of Antibody-Forming Capacity in Cultures of Nonadherent Spleen Cells by Mercaptoethanol
- 7 April 1972
- journal article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 176 (4030) , 60-61
- https://doi.org/10.1126/science.176.4030.60
Abstract
Populations of mouse spleen cells, without those cells that adhere to glass or plastic, exhibit little or no capacity for formation of antibody to sheep erythrocytes in the Mishell-Dutton culture system. When 5 x 10-5M mercaptoethanol is added to the culture medium, the antibody-forming capacity of these nonadherent spleen cells is restored to that of unfractionated spleen cells.Keywords
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