Prevalence and Inheritance of Factor XI (Plasma Thromboplastin Antecedent) Deficiency in Cattle
Open Access
- 1 April 1980
- journal article
- research article
- Published by American Dairy Science Association in Journal of Dairy Science
- Vol. 63 (4) , 616-620
- https://doi.org/10.3168/jds.s0022-0302(80)82980-8
Abstract
A survey of 169 Holstein-Friesian cattle showed 21 heterozygous for Factor XI activity having activities of .43 .+-. .10 units/ml compared with the normal .99 .+-. .32 units/ml. The frequency of the mutant gene was .06; the 95% confidence limits for the frequency of homozygotes in the population were .1-.8%, and for heterozygotes the frequency was 7.0-16.0%. Test matings indicated this disorder is transmitted as an autosomal recessive gene.This publication has 14 references indexed in Scilit:
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