Intravenous fusidic acid ('Fucidin') in the management of severe staphylococcal infections: a review of 46 cases
- 1 January 1976
- journal article
- case report
- Published by Taylor & Francis in Current Medical Research and Opinion
- Vol. 4 (2) , 132-138
- https://doi.org/10.1185/03007997609109293
Abstract
Case reports are reviewed of 46 patients with severe, life-threatening infections, mainly staphylococcal, who were treated with intravenous fusidic acid. Overall, 22 (48%) patients survived and 24 died, 10 of these within 24 hours of commencing treatment with fusidic acid. Thirty-nine patients received unsuccessful antibiotic therapy prior to the administration of fusidic acid. It was not possible to relate prior antibiotic treatment to outcome, and, in such severe infections, complicating diseases had an adverse effect upon survival. It is concluded that intravenous fusidic acid ('Fucidin') has an important place in the treatment of severe staphylococcal infections.Keywords
This publication has 12 references indexed in Scilit:
- Computer analyses of antibiotic sensitivities of bacteria isolated at Northwick Park Hospital during 1974Journal of Antimicrobial Chemotherapy, 1975
- Treatment of Late Endophthalmitis Associated With Filtering BlebsArchives of Ophthalmology (1950), 1974
- INTRAVENOUS FUSIDIC ACID IN THE NEWBORNThe Lancet, 1973
- Haematuria during methicillin therapyPublished by Oxford University Press (OUP) ,1971
- METHICILLIN-RESISTANT STAPHYLOCOCCIThe Lancet, 1968
- Fusidate Sodium in Treatment of Surgical InfectionsArchives of Surgery, 1968
- The stereochemistry of fusidic acidCellular and Molecular Life Sciences, 1964
- FUSIDIC ACID IN BACTERIAL ENDOCARDITISThe Lancet, 1962
- A CASE OF STAPHYLOCOCCAL SEPTICÆMIA TREATED WITH PENICILLIN AND FUCIDINThe Lancet, 1962
- FUCIDIN: A New Orally Active AntibioticThe Lancet, 1962