ADDISON'S DISEASE PRESENTING AS A HYPERCALCAEMIC CRISIS IN A PATIENT WITH IDIOPATHIC HYPOPARATHYROIDISM

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Abstract
A patient with idiopathic hypoparathyroidism complicated by Addison''s disease is described. The development of adrenal insufficiency was accompanied by a hypercalcemic crisis. The hypercalcemia appeared to result from a reduction in the filtered load and enhanced renal tubular reabsorption of Ca. Cortisone therapy was followed by the characteristic renal tubular Ca leak associated with hypoparathyroidism and a return of the serum Ca to normal. The possible mechanisms for these changes in Ca homeostasis are discussed.